Article
Clonal tests of conventional kinesin function during cell proliferation and differentiation.
Molecular biology of the cell - 1 Apr 2000
Brendza R P, Sheehan K B, Turner F R, Saxton W M
Abstract excerpt
Null mutations in the Drosophila Kinesin heavy chain gene (Khc), which are lethal during the second larval instar, have shown that conventional kinesin is critical for fast axonal transport in neurons, but its functions elsewhere are uncertain. To test other tissues, single imaginal cells in young larvae were rendered null for Khc by mitotic recombination. Surprisingly, the null cells produced large clones of...
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