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Article

Mutation of a gene for a Drosophila kinesin-like protein, Klp38B, leads to failure of cytokinesis.

Journal of cell science - 1 Apr 1997

Ohkura H, Török T, Tick G, Hoheisel J, Kiss I, Glover D M

Abstract excerpt

Mutations in a gene (Klp38B) encoding a novel kinesin-like protein in Drosophila melanogaster lead to the formation of polyploid cells in the larval central nervous system and in the follicle cells of adult egg chambers. Some homozygous mutants survive to adulthood and also exhibit morphological defects indicative of abnormal cell cycle progression, including rough eyes, missing bristles, and abnormal abdominal...

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Identifiers

PMID: 9152020
DOI: 10.1242/jcs.110.8.945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation of a gene for a Drosophila kinesin-like protein, Klp38B, leads to failure of cytokinesis.PMID 9152020Read ↗

A Drosophila kinesin-like protein, Klp38B, functions during meiosis, mitosis, and segmentation.Semantic proximity Read ↗

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pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

Novel nuclear defects in KLP61F-deficient mutants in Drosophila are partially suppressed by loss of Ncd function.Semantic proximity Read ↗

The Drosophila kinesin-like protein KLP3A is a midbody component required for central spindle assembly and initiation of cytokinesis.Semantic proximity Read ↗

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Loss of Drosophila borealin causes polyploidy, delayed apoptosis and abnormal tissue development.Semantic proximity Read ↗

HorkaD, a chromosome instability-causing mutation in Drosophila, is a dominant-negative allele of Lodestar.Semantic proximity Read ↗

The Drosophila kinesin-like protein KLP3A is required for proper behavior of male and female pronuclei at fertilization.Semantic proximity Read ↗

Mutations in Drosophila myb lead to centrosome amplification and genomic instability.Semantic proximity Read ↗

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