Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila.

doi:10.1093/genetics/142.1.195

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Article

Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila.

Genetics - 1 Jan 1996

Hurd D D, Stern M, Saxton W M

Abstract excerpt

To investigate the possibility that kinesin transports vesicles bearing proteins essential for ion channel activity, the effects of kinesin (Khc) and ion channel mutations were compared in Drosophila using established tests. Our results show that Khc mutations produce defects and genetic interact...

Topics

Animals
Axonal Transport
Crosses, Genetic
Drosophila
Female
Genes, Insect
Kinesins
Male
Mutation
Paralysis
Potassium Channels
Sodium Channels
Sodium-Potassium-Exchanging ATPase
Temperature

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