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Article

Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila.

Genetics - 1 Jan 1996

Hurd D D, Stern M, Saxton W M

Abstract excerpt

To investigate the possibility that kinesin transports vesicles bearing proteins essential for ion channel activity, the effects of kinesin (Khc) and ion channel mutations were compared in Drosophila using established tests. Our results show that Khc mutations produce defects and genetic interactions characteristic of paralytic (para) and maleless (mle) mutations that cause reduced expression or function of the...

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Identifiers

PMID: 8770597
DOI: 10.1093/genetics/142.1.195
PMCID: PMC1206948

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Source receipt: pubmed, retrieved 7 Sept 2026.

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