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Article

Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter.

The Journal of clinical investigation - 1 Apr 2000

Miyazaki Y, Oshima K, Fogo A, Hogan B L, Ichikawa I

Abstract excerpt

In the normal mouse embryo, Bmp4 is expressed in mesenchymal cells surrounding the Wolffian duct (WD) and ureter stalk, whereas bone morphogenetic protein (BMP) type I receptor genes are transcribed either ubiquitously (Alk3) or exclusively in the WD and ureter epithelium (Alk6). Bmp4 heterozygous null mutant mice display, with high penetrance, abnormalities that mimic human congenital anomalies of the kidney and...

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Source

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Identifiers

PMID: 10749566
DOI: 10.1172/JCI8256
PMCID: PMC377476

Genes

BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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