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Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling

18 Apr 2007

Abstract excerpt

Urinary tract morphogenesis requires the sub-division of the ureteric bud (UB) into the intra-renal collecting system and ureter, two tissues with unique structural and functional properties. In this report we investigate the cellular and molecular mechanisms that mediate their differentiation. Fate mapping experiments in the developing chick indicate that the UB is surrounded by two distinct mesenchymal...

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PMID: 17442697
DOI: 10.1242/dev.004234

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