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Article

Plakins, a versatile family of cytolinkers: roles in skin integrity and in human diseases.

The Journal of investigative dermatology - 1 Apr 2014

Bouameur Jamal-Eddine, Favre Bertrand, Borradori Luca

Abstract excerpt

The plakin family consists of giant proteins involved in the cross-linking and organization of the cytoskeleton and adhesion complexes. They further modulate several fundamental biological processes, such as cell adhesion, migration, and polarization or signaling pathways. Inherited and acquired defects of plakins in humans and in animal models potentially lead to dramatic manifestations in the skin, striated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24352042
DOI: 10.1038/jid.2013.498

Genes

MACF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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