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Article

Glucose and ras activity influence the ubiquitin ligases APC/C and SCF in Saccharomyces cerevisiae.

Genetics - 1 Apr 2000

Irniger S, Bäumer M, Braus G H

Abstract excerpt

In budding yeast, the Ras/cAMP pathway is involved in the coordination of cell growth and cell division. Glucose-rich medium stimulates Ras/cAMP signaling, which causes an increase in the critical cell size for cell cycle entry. Here we show that glucose and activated Ras proteins also influence the function of the anaphase-promoting complex (APC/C), a ubiquitin-protein ligase required for sister chromatid...

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Identifiers

PMID: 10747049
DOI: 10.1093/genetics/154.4.1509
PMCID: PMC1461040

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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