Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1.

Molecular and cellular biology - 1 Mar 2001

Johnston S D, Enomoto S, Schneper L, McClellan M C, Twu F, Montgomery N D, Haney S A, Broach J R, Berman J

Abstract excerpt

Cac3p/Msi1p, the Saccharomyces cerevisiae homolog of retinoblastoma-associated protein 48 (RbAp48), is a component of chromatin assembly factor I (CAF-I), a complex that assembles histones H3 and H4 onto replicated DNA. CAC3 overexpression also suppresses the RAS/cyclic AMP (cAMP) signal transduction pathway by an unknown mechanism. We investigated this mechanism and found that CAC3 suppression of RAS/cAMP signal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Galactose

Share to Hot Temperature

Share to Luminescent Proteins

Share to Precipitin Tests

Share to Suppression, Genetic

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 11238915
DOI: 10.1128/MCB.21.5.1784-1794.2001
PMCID: PMC86735

Genes

NPR1
MSI1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1.PMID 11238915Read ↗

Chromatin assembly factor I mutants defective for PCNA binding require Asf1/Hir proteins for silencing.Semantic proximity Read ↗

A conserved family of WD-40 proteins binds to the retinoblastoma protein in both plants and animals.Semantic proximity Read ↗

CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.Semantic proximity Read ↗

Glucose and ras activity influence the ubiquitin ligases APC/C and SCF in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.Semantic proximity Read ↗

Mutual interdependence of MSI1 (CAC3) and YAK1 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Crosstalk between the Ras2p-controlled mitogen-activated protein kinase and cAMP pathways during invasive growth of Saccharomyces cerevisiae.Semantic proximity Read ↗

Contribution of CAF-I to anaphase-promoting-complex-mediated mitotic chromatin assembly in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of cyclin B2 expression and cell cycle G2/m transition by menin.Semantic proximity Read ↗

A cytoskeletal localizing domain in the cyclase-associated protein, CAP/Srv2p, regulates access to a distant SH3-binding site.Semantic proximity Read ↗

Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57 KIP2 requires binding to proliferating cell nuclear antigenSemantic proximity Read ↗

Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.