Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impaired proteasome function rescues thermosensitivity of yeast cells lacking the coatomer subunit epsilon-COP.

The Journal of biological chemistry - 7 Apr 2000

Kimata Y, Higashio H, Kohno K

Abstract excerpt

Formation of COPI-coated transport vesicles requires a cytosolic protein complex consisting of seven subunits: alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP, collectively designated coatomer. The yeast Saccharomyces cerevisiae gene encoding the epsilon-COP subunit is known as SEC28/ANU2. anu2 null mutant cells (anu2Delta) are temperature-sensitive, and alpha-COP is rapidly degraded in these cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Coatomer Protein
Share to Cysteine Endopeptidases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cysteine Proteinase Inhibitors

Share to Leupeptins

Share to Macromolecular Substances

Share to Multienzyme Complexes

Share to Suppression, Genetic

Source

Identifiers

PMID: 10744762
DOI: 10.1074/jbc.275.14.10655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impaired proteasome function rescues thermosensitivity of yeast cells lacking the coatomer subunit epsilon-COP.PMID 10744762Read ↗

epsilon-COP is a structural component of coatomer that functions to stabilize alpha-COP.Semantic proximity Read ↗

Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic.Semantic proximity Read ↗

Disruption of Rpn4-Induced Proteasome Expression in Saccharomyces cerevisiae Reduces Cell Viability Under Stressed ConditionsSemantic proximity Read ↗

The exocyst subunit Sec3 is regulated by a protein quality control pathway.Semantic proximity Read ↗

An Inducible Chaperone Adapts Proteasome Assembly to StressSemantic proximity Read ↗

Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function.Semantic proximity Read ↗

A genetic link between the unfolded protein response and vesicle formation from the endoplasmic reticulum.Semantic proximity Read ↗

Deletion of PIN4 Suppresses the Protein Transport Defects Caused by sec12-4 Mutation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Evidence for the intimate relationship between vesicle budding from the ER and the unfolded protein response.Semantic proximity Read ↗

Mutational analysis reveals a role for the C terminus of the proteasome subunit Rpt4p in spindle pole body duplication in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutations in the yeast proteasome beta-type subunit Pre3 uncover position-dependent effects on proteasomal peptidase activity and in vivo function.Semantic proximity Read ↗

COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.