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Article

Fibrinolytic proteins and progression of coronary artery disease in relation to gemfibrozil therapy.

Thrombosis and haemostasis - 1 Mar 2000

Hamsten A, Syvänne M, Silveira A, Luong L A, Nieminen M S, Humphries S, Frick M H, Taskinen M R

Abstract excerpt

Impaired fibrinolytic function, mainly due to increased plasma plasminogen activator inhibitor-1 (PAI-1) activity, is common in patients with manifest coronary artery disease (CAD) and a predictor of recurrent cardiovascular events. We investigated the relationships of plasma tissue-type plasminogen activator (tPA) and PAI-1 antigen levels, plasma PAI-1 activity and PAI 4/5-guanosine (4G/5G) genotype to CAD...

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PMID: 10744143

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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