Article
-455G/A polymorphism of the beta-fibrinogen gene is associated with the progression of coronary atherosclerosis in symptomatic men: proposed role for an acute-phase reaction pattern of fibrinogen. REGRESS group.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 1998
de Maat M P, Kastelein J J, Jukema J W, Zwinderman A H, Jansen H, Groenemeier B, Bruschke A V, Kluft C
Abstract excerpt
Increased plasma fibrinogen levels have been identified as a risk indicator for myocardial infarction, stroke, and thrombosis. Both environmental and genetic factors make an important contribution to plasma fibrinogen levels in humans. In the present study we evaluated, in patients with serum cholesterol levels between 4 and 8 mmol/L, the relation of plasma levels and polymorphisms of fibrinogen with coronary...
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