Article
Plasminogen activator inhibitor-1 and outcome after femoropopliteal angioplasty: analysis of genotype and plasma levels.
Thrombosis and haemostasis - 1 Oct 2003
Mlekusch Wolfgang, Schillinger Martin, Exner Markus, Sabeti Schila, Mannhalter Christine, Minar Erich, Wagner Oswald
Abstract excerpt
Plasminogen activator inhibitor-1 (PAI-1) is suggested to be involved in the pathophysiology of early thrombosis and late restenosis after percutaneous transluminal angioplasty (PTA). The role of the PAI-1 promoter genotype in this context is indeterminate. We investigated the association of the (4G/5G) polymorphism at nucleotide position (-675) in the PAI-1 gene promoter, PAI-1 plasma levels, and postangioplasty...
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