Article
The G20210A prothrombin polymorphism is not associated with increased thromboembolic risk in a large protein C deficient kindred.
Thrombosis and haemostasis - 1 Mar 2000
Bovill E G, Hasstedt S J, Callas P W, Valliere J E, Scott B T, Bauer K A, Long G L
Abstract excerpt
Likelihood analysis was used to test the effect of the G20210A prothrombin mutation and the His107Pro protein C mutation (resulting from a C insertion) on thrombosis status and prothrombin level in a large kindred of French Canadian descent with type I protein C deficiency. Genotypes were available on 279 pedigree members or their spouses. Of this total, 36 pedigree members were heterozygous for the G20210A...
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