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Article

Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2000

Jönsson M, Borg A, Nilbert M, Andersson T

Abstract excerpt

We studied the relevance of adenomatous polyposis coli (APC)/beta-catenin signalling in the development of breast cancer by analysing the expression of beta-catenin in 54 primary breast tumours (34 ductal and 20 lobular). We showed that 13% of the tumours exhibited upregulated levels of beta-catenin in the cytosol suggesting that defects in APC/beta-catenin signalling components had lowered the rate of...

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Source

Identifiers

PMID: 10741284
DOI: 10.1016/s0959-8049(99)00276-2

Genes

APC
MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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