Article
Supportive evidence for contribution of the dopamine D2 receptor gene to heritability of stature: linkage and association studies.
Annals of human genetics - 1 Mar 1999
Arinami T, Iijima Y, Yamakawa-Kobayashi K, Ishiguro H, Ohtsuki T, Yanagi H, Shimakura Y, Ishikawa H, Hamaguchi H
Abstract excerpt
Increases in height were reported in children chronically exposed prenatally and postnatally to D2 receptor-blocking drugs. A possible haplotypic association between stature and the DRD2 gene was also reported. In this study, we examined linkage between stature and DRD2 by genotyping a dinucleotide repeat polymorphism in 79 sib-pairs aged 8-17 years. An association between stature and a putative functional...
Topics
- Adolescent
- Adult
- Body Height
- Body Mass Index
- Child
- Cholesterol
- DNA
- Dinucleotide Repeats
- Female
- Genetic Linkage
- Genotype