Article
Vitamin D receptor gene polymorphisms are linked to and associated with adult height.
Journal of medical genetics - 1 Mar 2005
Xiong D-H, Xu F-H, Liu P-Y, Shen H, Long J-R, Elze L, Recker R R, Deng H-W
Abstract excerpt
BACKGROUND: The vitamin D receptor (VDR) gene is important to human stature, as it mediates metabolic pathways, calcium homeostasis, and phosphate homeostasis, which influence growth. METHODS: We examined the relationship between VDR and adult height in 1873 white subjects from 406 nuclear families. Four SNPs, namely -4817A/G at intron 1, FokI C/T at exon 2 start codon, BsmI A/G at intron 8, and TaqI T/C at exon...
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