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Article

Transcriptional control of multidrug resistance in the yeast Saccharomyces.

Progress in nucleic acid research and molecular biology - 1 Jan 2003

Moye-Rowley W Scott

Abstract excerpt

A major problem in chemotherapeutic treatment of many pathological conditions including cancer and fungal infections is the development of a multidrug-resistant state in the target cell. Saccharomyces cerevisiae cells can be isolated that have single genetic alterations that cause the resulting mutant strains to become tolerant of a wide range of compounds that would otherwise be toxic. These mutant cells are...

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PMID: 12882520
DOI: 10.1016/s0079-6603(03)01008-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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