Article
A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival.
Biochemical and biophysical research communications - 2 Apr 2000
Ji H, Zhai Q, Zhu J, Yan M, Sun L, Liu X, Zheng Z
Abstract excerpt
To find a possible signal interacting with the Jak3 N-terminal, we screened the human peripheral blood cDNA library through both a two-hybrid system and a tyrosine-phosphorylation-modified two-hybrid system using the N-terminal of Jak3 as bait. Results showed that one new homologue of myosin heavy chain, designated MAJN (molecule associated with Jak3 N-terminal), could bind to Jak3 in a...
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