Article
Phenotypic and functional characteristics of hematopoietic cell lineages in CD69-deficient mice.
Blood - 1 Apr 2000
Lauzurica P, Sancho D, Torres M, Albella B, Marazuela M, Merino T, Bueren J A, Martínez-A C, Sánchez-Madrid F
Abstract excerpt
AIM/CD69 is the earliest leukocyte activation antigen and is expressed mainly by activated T, B, and natural killer (NK) cells. It is also constitutively expressed by platelets, by bone marrow myeloid precursors, and by small subsets of resident lymphocytes in the secondary lymphoid tissues. The engagement of CD69 by specific antibodies induces intracellular signals, including Ca(++) flux, cytokine synthesis, and...
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