Article
Analysis of radon-associated squamous cell carcinomas of the lung for a p53 gene hotspot mutation.
British journal of cancer - 1 Feb 2000
Yang Q, Wesch H, Mueller K M, Bartsch H, Wegener K, Hollstein M
Abstract excerpt
Squamous cell lung carcinomas (SCC) from former employees of the Wismut uranium mining company (Saxony, Germany) were obtained from the Stollberg Archive in order to screen for p53 tumour suppressor gene codon 249 arg-->met hotspot mutations, a putative molecular bio-dosimeter of alpha-particle (radon) exposure (Taylor et al (1994) Lancet 343: 86-87; McDonald et al (1995) Cancer Epidemiol Biomarkers Prevent 4:...
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