Article
ATM gene mutations in former uranium miners of SDAG Wismut: a pilot study.
Oncology reports - 1 Feb 2007
Schneider Joachim, Philipp Monika, Yamini Paria, Dörk Thilo, Woitowitz Hans-Joachim
Abstract excerpt
Ataxia-telangiectasia is an autosomal recessive disease characterized by neurological and immunological symptoms, radiosensitivity and cancer predisposition. Heterozygous carriers of an ataxia-telangiectasia gene mutation are predisposed to epithelial cancers. We initiated a study to elucidate the frequency and clinical relevance of ATM gene mutations in former uranium miners exposed to high levels of radiation...
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