Article
Linkage analysis in the presence of errors III: marker loci and their map as nuisance parameters.
American journal of human genetics - 1 Apr 2000
Göring H H, Terwilliger J D
Abstract excerpt
In linkage and linkage disequilibrium (LD) analysis of complex multifactorial phenotypes, various types of errors can greatly reduce the chance of successful gene localization. The power of such studies-even in the absence of errors-is quite low, and, accordingly, their robustness to errors can be poor, especially in multipoint analysis. For this reason, it is important to deal with the ramifications of errors up...
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