Article
Polymorphisms in xenobiotic metabolism-related genes in patients with hepatocellular carcinoma: a case-control study.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Jun 2021
Ferreira Gislaine Dionísio, Fernandes Glaucia Maria de Mendonça, Penteado Camila, Cória Vivian Romanholi, Galbiatti-Dias Ana Lívia da Silva, Russo Anelise, Castanhole-Nunes Márcia Maria Urbanin, Silva Renato Ferreira da, Silva Rita de Cássia Martins Alves da, Pavarino Érika Cristina, Torreglosa Ruiz Cintra Mariangela, Goloni-Bertollo Eny Maria
Abstract excerpt
This study was performed to investigate the relationship between polymorphisms in microsomal epoxide hydrolase (mEH; Tyr113His and His139Arg substitution) and glutathione S-transferase (GST; GSTM1 deletion, GSTT1 deletion, and GSTP1.Ala114Val substitution) and their correlation with clinico-histopathological features in hepatocellular carcinoma (HCC).We evaluated environmental risk factors and genetic alterations...
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