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Article

Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation.

Genome research - 1 Mar 2000

Mein C A, Barratt B J, Dunn M G, Siegmund T, Smith A N, Esposito L, Nutland S, Stevens H E, Wilson A J, Phillips M S, Jarvis N, Law S, de Arruda M, Todd J A

Abstract excerpt

Large-scale pharmacogenetics and complex disease association studies will require typing of thousands of single-nucleotide polymorphisms (SNPs) in thousands of individuals. Such projects would benefit from a genotyping system with accuracy >99% and a failure rate <5% on a simple, reliable, and flexible platform. However, such a system is not yet available for routine laboratory use. We have evaluated a...

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Identifiers

PMID: 10720574
DOI: 10.1101/gr.10.3.330
PMCID: PMC311429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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