Article
Invader assay for single-nucleotide polymorphism genotyping and gene copy number evaluation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006
Mast Andrea, de Arruda Monika
Abstract excerpt
The Invader assay (Third Wave Technologies) is a homogeneous, isothermal DNA probe-based method for sensitive detection of nucleic acid sequences. Invader reactions are performed directly on genomic DNA or total RNA targets; however, polymerase chain reaction- or reverse transcriptase polymerase chain re action-amplified products can also be used. Detection is achieved through target-specific signal amplification...
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