Article
HLA and other host factors in transfusion-acquired HIV-1 infection.
Human immunology - 1 Feb 2000
Geczy A F, Kuipers H, Coolen M, Ashton L J, Kennedy C, Ng G, Dodd R, Wallace R, Le T, Raynes-Greenow C H, Dyer W B, Learmont J C, Sullivan J S
Abstract excerpt
The host and viral factors that underlie infection with HIV-1 vary considerably with some individuals progressing to AIDS within 3 to 5 years after infection, whereas others remain clinically asymptomatic for over 10 years. Host factors that may contribute to disease progression include HLA and allelic variants of the chemokine receptors CCR5 and CCR2, which have been shown to influence both long-term survival...
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