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Article

Promoter-proximal pausing on the hsp70 promoter in Drosophila melanogaster depends on the upstream regulator.

Molecular and cellular biology - 1 Apr 2000

Tang H, Liu Y, Madabusi L, Gilmour D S

Abstract excerpt

RNA polymerase II pauses in the promoter-proximal region of many genes during transcription. In the case of the hsp70 promoter from Drosophila melanogaster, this pause is long-lived and occurs even when the gene is not induced. Paused polymerase escapes during heat shock when the transcriptional activator heat shock factor associates with the promoter. However, pausing is still evident, especially when induction...

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Source

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Identifiers

PMID: 10713179
DOI: 10.1128/MCB.20.7.2569-2580.2000
PMCID: PMC85473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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