Article
Afferent-specific modulation of short-term synaptic plasticity by neurotrophins in dentate gyrus.
The European journal of neuroscience - 1 Feb 2000
Asztely F, Kokaia M, Olofsdotter K, Ortegren U, Lindvall O
Abstract excerpt
Neurotrophins modulate synaptic transmission and plasticity in the adult brain. We here show a novel feature of this synaptic modulation, i.e. that two populations of excitatory synaptic connections to granule cells in the dentate gyrus, lateral perforant path (LPP) and medial perforant path (MPP), are differentially influenced by the neurotrophins BDNF and NT-3. Using field recordings and whole-cell patch-clamp...
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