Article
Coding single nucleotide polymorphism in the high-affinity immunoglobulin E receptor b chain (FcepsilonRI-beta) gene is associated with immunoglobulin E receptor-mediated histamine release from basophils.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 2002
Kim Y-K, Oh S-Y, Oh H-B, Chun S-Y, Cho S-H, Koh Y-Y, Min K-U, Kim Y-Y
Abstract excerpt
BACKGROUND: Our previous work on linkage analysis showed that histamine release from basophils to anti-IgE stimuli was linked to the gene marker of chromosome 11q13, where the beta chain of the high-affinity receptor for IgE (FcepsilonRI-beta) is located. OBJECTIVE: To evaluate the association between FcepsilonRI-mediated histamine release from basophils and four bi-allelic single nucleotide polymorphisms of the...
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