Article
Characterization of inducible nature of MRP3 in rat liver.
American journal of physiology. Gastrointestinal and liver physiology - 1 Mar 2000
Ogawa K, Suzuki H, Hirohashi T, Ishikawa T, Meier P J, Hirose K, Akizawa T, Yoshioka M, Sugiyama Y
Abstract excerpt
We found previously that expression of multidrug resistance-associated protein (MRP) 3 is induced in a mutant rat strain (Eisai hyperbilirubinemic rats) whose canalicular multispecific organic anion transporter (cMOAT/MRP2) function is hereditarily defective and in normal Sprague-Dawley (SD) rats after ligation of the common bile duct. In the present study, the inducible nature of MRP3 was examined, using...
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