Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Statistical tests for detection of misspecified relationships by use of genome-screen data.

American journal of human genetics - 1 Mar 2000

McPeek M S, Sun L

Abstract excerpt

Misspecified relationships can have serious consequences for linkage studies, resulting in either reduced power or false-positive evidence for linkage. If some individuals in the pedigree are untyped, then Mendelian errors may not be observed. Previous approaches to detection of misspecified relationships by use of genotype data were developed for sib and half-sib pairs. We extend the likelihood calculations of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Mapping
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Testing

Share to Genotype

Share to Microsatellite Repeats

Share to Models, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 10712219
DOI: 10.1086/302800
PMCID: PMC1288143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Statistical tests for detection of misspecified relationships by use of genome-screen data.PMID 10712219Read ↗

Reconciling the analysis of IBD and IBS in complex trait studies.Semantic proximity Read ↗

Detection of inappropriate samples in association studies by an IBS-based method considering linkage disequilibrium between genetic markers.Semantic proximity Read ↗

Probabilities of two alleles being identity by state at unobserved loci predicted by observed loci in cattle populations.Semantic proximity Read ↗

Genotyping errors, pedigree errors, and missing data.Semantic proximity Read ↗

A normalized identity-by-state statistic for linkage analysis of sib pairs.Semantic proximity Read ↗

Prediction of multilocus identity-by-descent.Semantic proximity Read ↗

Relationship estimation in affected sib pair analysis of late-onset diseases.Semantic proximity Read ↗

Potential bias in Generalized Estimating Equations linkage methods under incomplete information.Semantic proximity Read ↗

Using identity-by-descent information in affected sib pairs to increase the efficiency of genetic association studies.Semantic proximity Read ↗

Linkage analysis of alcohol dependence using both affected and discordant sib pairs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.