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Article

Statistical tests for detection of misspecified relationships by use of genome-screen data.

American journal of human genetics - 1 Mar 2000

McPeek M S, Sun L

Abstract excerpt

Misspecified relationships can have serious consequences for linkage studies, resulting in either reduced power or false-positive evidence for linkage. If some individuals in the pedigree are untyped, then Mendelian errors may not be observed. Previous approaches to detection of misspecified rela...

Topics

Alcoholism
Alleles
Chromosome Mapping
Computer Simulation
Consanguinity
Female
Gene Frequency
Genetic Testing
Genome, Human
Genotype
Humans
Likelihood Functions
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Markov Chains

Matched-Pair Analysis

Microsatellite Repeats

Models, Genetic

Nuclear Family

Source

Open in PubMed Open full text

Identifiers

PMID: 10712219
DOI: 10.1086/302800
PMCID: PMC1288143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-10712219-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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