Article
Involvement of NF-kappaB associated proteins in FGF-mediated mesoderm induction.
The International journal of developmental biology - 1 Jan 1998
Beck C W, Sutherland D J, Woodland H R
Abstract excerpt
In this report, we have used mRNA injection to study the action of mutants of XrelA, a Xenopus homolog of the RelA (p65) component of NF-kappaB, on the induction of mesoderm in Xenopus embryos. A region of the rel homology domain of XrelA was deleted to create XrelA deltaSP, which retains the dimerization and activation domains, but no longer binds to DNA. We also made an analogous derivative of mammalian...
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