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Article

Role of ribosome and translocon complex during folding of influenza hemagglutinin in the endoplasmic reticulum of living cells.

Molecular biology of the cell - 1 Feb 2000

Chen W, Helenius A

Abstract excerpt

Protein folding in the living cell begins cotranslationally. To analyze how it is influenced by the ribosome and by the translocon complex during translocation into the endoplasmic reticulum, we expressed a mutant influenza hemagglutinin (a type I membrane glycoprotein) with a C-terminal extension. Analysis of the nascent chains by two-dimensional SDS-PAGE showed that ribosome attachment as such had little effect...

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Identifiers

PMID: 10679029
DOI: 10.1091/mbc.11.2.765
PMCID: PMC14808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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