GroEL and GroES control of substrate flux in the in vivo folding pathway of phage P22 coat protein.

doi:10.1074/jbc.273.42.27236

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Article

GroEL and GroES control of substrate flux in the in vivo folding pathway of phage P22 coat protein.

The Journal of biological chemistry - 16 Oct 1998

Nakonechny W S, Teschke C M

Abstract excerpt

Our present understanding of the action of the chaperonins GroEL/S on protein folding is based primarily on in vitro studies, whereas the folding of proteins in the cellular milieu has not been as thoroughly investigated. We have developed a means of examining in vivo protein folding and assembly...

Topics

Bacteriophage P22
Capsid
Chaperonin 10
Chaperonin 60
Escherichia coli
Models, Biological
Mutation
Phenotype
Protein Binding
Protein Folding
Salmonella typhimurium
Temperature

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