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Article

Quantitative assessment of apolipoprotein E genotypes by image analysis of PCR-RFLP fragments.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2000

Wu Y Y, Delgado R, Costello R, Sunderland T, Dukoff R, Csako G

Abstract excerpt

Apolipoprotein E (APOE) genotyping usually involves polymerase chain reaction (PCR) and assessment of restriction fragment length polymorphism (RFLP) by gel electrophoresis. We made determination of HhaI restriction endonuclease digestive patterns more objective and improved diagnostic accuracy with a quantitative approach using sensitive DNA stain (SYBR Green) and image analysis of gel patterns. For...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10699435
DOI: 10.1016/s0009-8981(99)00237-5

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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