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Article

High-throughput sequence typing of T-cell epitope polymorphisms in Plasmodium falciparum circumsporozoite protein.

Molecular and biochemical parasitology - 5 Mar 2000

Alloueche A, Silveira H, Conway D J, Bojang K, Doherty T, Cohen J, Pinder M, Greenwood B M

Abstract excerpt

We report a method for typing polymorphisms at the T-cell epitopes within the Th2R and Th3R regions of the Plasmodium falciparum circumsporozoite protein (CSP). This method combines the use of PCR and sequence specific oligonucleotide probes (PCR-SSOP), and allows the identification of single nucleotide polymorphisms in these epitope regions. PCR-SSOP is a robust and a high-throughput sequence typing technique...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10699256
DOI: 10.1016/s0166-6851(99)00221-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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