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Article

Decreased transport of leptin across the blood-brain barrier in rats lacking the short form of the leptin receptor.

Peptides - 1 Dec 1999

Kastin A J, Pan W, Maness L M, Koletsky R J, Ernsberger P

Abstract excerpt

Leptin is produced in adipose tissue in the periphery, but its satiety effect is exerted in the CNS that it reaches by a saturable transport system across the blood-brain barrier (BBB). The short form of the leptin receptor has been hypothesized to be the transporter, with impaired transport of l...

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Source

Identifiers

PMID: 10698121
DOI: 10.1016/s0196-9781(99)00156-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10698121-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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