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Article

Establishment and characterization of cell lines from chromosomal instable colorectal cancer.

World journal of gastroenterology - 7 Jan 2015

Maletzki Claudia, Gock Michael, Randow Martin, Klar Ernst, Huehns Maja, Prall Friedrich, Linnebacher Michael

Abstract excerpt

AIM: To generate novel tumor models for preclinical validation of biomarkers that allow drug response prediction and individual therapeutic decisions. METHODS: Cell line establishment was conducted by both direct in vitro culturing and in vivo xenografting followed by in vitro culturing procedure. A comprehensive characterization was subsequently performed. This included quality control, consisting of the...

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PMID: 25574089
DOI: 10.3748/wjg.v21.i1.164
PMCID: PMC4284332

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