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Article

p53-dependent apoptosis in melanoma cells after treatment with camptothecin.

The Journal of investigative dermatology - 1 Mar 2000

Li G, Bush J A, Ho V C

Abstract excerpt

Cutaneous malignant melanoma is a life-threatening cancer with poor prognosis due to a high metastasis potential. The main obstacle in treatment of metastatic melanoma is the resistance to chemotherapy. Recent studies indicated that apoptosis is a common mechanism of action for various cytotoxic agents. As p53 plays an important part in apoptosis, we investigated the role of p53 in chemosensitivity of melanoma...

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Share to Antineoplastic Agents, Phytogenic
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to bcl-2 Homologous Antagonist-Killer Protein

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Source

Identifiers

PMID: 10692111
DOI: 10.1046/j.1523-1747.2000.00867.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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