Article
Chemotherapy-induced apoptosis in melanoma cells is p53 dependent.
Melanoma research - 1 Feb 1998
Li G, Tang L, Zhou X, Tron V, Ho V
Abstract excerpt
Metastatic melanomas are often resistant to chemotherapy. To study whether the p53 mutational status affects chemosensitivity, we compared the responses to chemotherapy of four melanoma cell lines containing the wild-type p53 and four cell lines carrying the mutant p53. Cisplatin, at 10 microM, v...
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