Article
No longer a molecular black box--new clues to apoptosis and drug resistance in melanoma.
Trends in molecular medicine - 1 May 2001
Satyamoorthy K, Bogenrieder T, Herlyn M
Abstract excerpt
Disseminated melanoma is a radiation- and chemotherapy-refractory neoplasm for which no standard therapy currently exists. So far, genetic and molecular studies have revealed few non-random chromosomal abnormalities and infrequent mutational spectra. Consequently, the precise molecular determinants responsible for melanoma progression are yet to be delineated. Recent studies, however, have identified defects at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.