Article
Dyserythropoiesis associated with a fas-deficient condition in childhood.
British journal of haematology - 1 Feb 2000
Bader-Meunier B, Rieux-Laucat F, Croisille L, Yvart J, Mielot F, Dommergues J P, Ledeist F, Tchernia G
Abstract excerpt
Defective lymphocyte apoptosis caused by mutations of the Fas gene can result in an autoimmune lymphoproliferative syndrome (ALPS) in humans. We report two cases of dyserythropoiesis associated with a Fas-deficient condition in childhood. In both cases, dyserythropoiesis predominated on the more mature erythroblasts, and was associated with a lymphoproliferative syndrome as well as with haemolytic anaemia,...
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