Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Auto-immune hemolytic anemia and dyserythropoïesis as the presenting signs of Fas-deficient condition in 3 children].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie - 1 Apr 2006

Guitton C, Ledeist F, Tchernia G, Bader-Meunier B

Abstract excerpt

Defective apoptosis caused by mutations of the Fas gene can lead to an autoimmune lymphoproliferative syndrome (ALPS). The main autoimmune manifestations are haematological: hemolytic anemia, thrombocytopenia and neutropenia. We described 3 patients with ALPS presenting as a lymphoproliferative syndrome associated with a Coomb's negative autoimmune hemolytic anemia and dyserythropoiesis predominating on the more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Dyserythropoietic, Congenital
Share to Anemia, Hemolytic, Autoimmune

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apoptosis

Share to Child, Preschool

Share to fas Receptor

Share to Hepatomegaly

Share to Infant

Share to Splenomegaly

Source

Identifiers

PMID: 16524705
DOI: 10.1016/j.arcped.2006.01.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Auto-immune hemolytic anemia and dyserythropoïesis as the presenting signs of Fas-deficient condition in 3 children].PMID 16524705Read ↗

Dyserythropoiesis associated with a fas-deficient condition in childhood.Semantic proximity Read ↗

[Autoimmune lymphoproliferative syndrome: molecular diagnosis in two families].Semantic proximity Read ↗

Clinical, immunological, and pathological consequences of Fas-deficient conditions.Semantic proximity Read ↗

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis.Semantic proximity Read ↗

Missense Mutations in the Fas Gene Resulting in Autoimmune Lymphoproliferative Syndrome: A Molecular and Immunological AnalysisSemantic proximity Read ↗

Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations.Semantic proximity Read ↗

Clinical, Immunologic, and Genetic Features of an Autoimmune Lymphoproliferative Syndrome Associated With Abnormal Lymphocyte ApoptosisSemantic proximity Read ↗

A homozygous Fas ligand gene mutation in a patient causes a new type of autoimmune lymphoproliferative syndromeSemantic proximity Read ↗

A new disorder of lymphocyte apoptosis: combination of autoimmunity, infectious lymphadenopathy, double negative T cells, and impaired activation-induced cell death.Semantic proximity Read ↗

Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder.Semantic proximity Read ↗

Autoimmune lymphoproliferative syndrome with somatic Fas mutations.Semantic proximity Read ↗

FAS-L, IL-10, and double-negative CD4- CD8- TCR alpha/beta+ T cells are reliable markers of autoimmune lymphoproliferative syndrome (ALPS) associated with FAS loss of function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.