Article
Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori.
Microbiology (Reading, England) - 1 Sept 1998
Bereswill Stefan, Waidner Uta, Odenbreit Stefan, Lichte Flavia, Fassbinder Frank, Bode G Nter, Kist Manfred
Abstract excerpt
The function of the pfr gene encoding the ferritin from Helicobacter pylori was investigated using the Fur titration assay (FURTA) in Escherichia coli, and by characterization of a pfr-deficient mutant strain of H. pylori. Nucleotide sequence analysis revealed that the pfr region is conserved among strains (> 95% nucleotide identity). Two transcriptional start sites, at least one of them preceded by a sigma...
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