Article
Mutation analysis of BRCA1, TP53, and KRAS2 in ovarian and related pelvic tumors.
Cancer genetics and cytogenetics - 15 Jul 1999
Tworek H, Peng R, Fetzer S, Werness B A, Piver M S, Allen H J, DiCioccio R A
Abstract excerpt
Cancer may be viewed as a genetic disease resulting from critical mutations that disrupt normal cell growth. To characterize the involvement of the BRCA1 and TP53 tumor suppressor genes and of the KRAS2 protooncogene in gynecologic cancer, mutation analysis of these genes was conducted in pelvic tumors of 85 patients that included 49 epithelial ovarian carcinoma cases. The 85 pelvic tumors contained 5 tumors with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.