Article
Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu.
Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2009
Hakim Amy A, Barry Catherine P, Barnes H John, Anderson Kenneth E, Petitte James, Whitaker Regina, Lancaster Jonathan M, Wenham Robert M, Carver Donna K, Turbov Jane, Berchuck Andrew, Kopelovich Levy, Rodriguez Gustavo C
Abstract excerpt
We examined alterations in the p53 tumor suppressor gene and the ras and HER-2/neu oncogenes in chicken ovarian cancers to determine if these tumors have genetic alterations similar to those in human ovarian adenocarcinomas. Mutations in the p53 tumor suppressor gene and the H-ras and K-ras oncog...
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