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Article

A new double-stranded RNA-binding protein that interacts with PKR.

Nucleic acids research - 15 Mar 2000

Coolidge C J, Patton J G

Abstract excerpt

We have identified a 74 kDa double-stranded (ds)RNA-binding protein that shares extensive homology with the mouse spermatid perinuclear RNA-binding (Spnr) protein. p74 contains two dsRNA-binding motifs (dsRBMs) that are essential for preferential binding to dsRNA. Previously, dsRNA-binding proteins were shown to undergo homo- and heterodimerization, raising the possibility that regulation of activity could be...

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Identifiers

PMID: 10684936
DOI: 10.1093/nar/28.6.1407
PMCID: PMC111047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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