Article

The Human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2

2014-03-28

Abstract excerpt

The dsRNA binding protein (dsRBP) PACT was first described as an activator of the dsRNA dependent protein kinase PKR in response to stress signals. Additionally, it has been identified as a component of the small RNA processing pathway. A role for PACT in this pathway represents an important interplay between two modes of post-transcriptional gene regulation. The function of PACT in this context is poorly under...

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Literature Corpus work: d4f75393-535c-556b-97d0-807aefca82f5
DOI: 10.12688/f1000research.2-220.v2

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