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Article

Muscular dystrophy in adult and aged anti-NGF transgenic mice resembles an inclusion body myopathy.

Journal of neuroscience research - 15 Feb 2000

Capsoni S, Ruberti F, Di Daniel E, Cattaneo A

Abstract excerpt

The role of nerve growth factor (NGF) and its receptors in the physiology of skeletal muscles has not been extensively studied in animal models. We describe the production of transgenic lines of mice expressing a neutralizing antibody against NGF (alphaD11) and the morphological and histochemical analysis of skeletal muscles from adult and aged anti-NGF mice. This study reveals that the chronic deprivation of NGF...

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Source

Identifiers

PMID: 10679795
DOI: 10.1002/(SICI)1097-4547(20000215)59:4<553::AID-JNR11>3.0.CO;2-4

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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