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Article

Biochemical analysis of mutations at tyrosine-98 of the S1 subunit of pertussis toxin.

Biochemistry - 15 Feb 1994

Xu Y, Barbieri J T

Abstract excerpt

Molecular modeling and alignment of the primary amino acid sequence of the S1 subunit (S1) of pertussis toxin (PT) with other members of the family of ADP-ribosylating bacterial exotoxins predicted that tyrosine-98 (Y98) of S1 was a conserved residue among these exotoxins. To extend our understanding of the relationship between pertussis toxin and the other ADP-ribosylating exotoxins, we defined the function of...

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PMID: 8312278
DOI: 10.1021/bi00172a038

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